Juan L. Ribes "Radiation Oncology Nursing Consultation Coordinator" ICO Barcelona.

From January to December 2020.

Prevention and treatment of induced radiodermatitis is an unavoidable adverse effect. It is minimized with the care of nurses and the use of appropriate products. In this document we present a test to know in depth the effectiveness of GGcare products.

The combination of Soothing Body Cream and Soothing Repairing Oil is a highly recommended protocol for the prevention and reduction of radiodermatitis in breast cancer.

Fourteen patients with breast cancer who underwent onco-radiotherapy treatments were studied and divided into two subgroups: normofractionated (25 sessions of 50 Gy) and hypofractionated (15 sessions of 40.05 Gy). This division is made because the skin reactions are different in the presentation times.

loss of 2.8% from the beginning to the end of treatment. Average loss of other creams 10%.

loss of 5.66% from start to end of treatment. Average loss with other creams 10-12%.

7.5% increase from start to end of treatment. Average increase for other creams 12-18%.

increase 22.08% from start to end of treatment. Average increase of other creams 15-25%.

loss of 11.3% from the beginning to the end of treatment. Average loss of other creams 10%.

2% loss from start to finish of treatment. Average loss of other creams 10-12%.

loss 1.1% from start to end of treatment. Average increase with other creams 12-18%.

20% increase from start to end of treatment. Average increase of other creams 15-25%.

Different reactions are observed between normo and hypo. This is due to the difference in dose/session. The loss of elasticity increases in hypo; however, it protects better against loss of hydration and good aesthetic results with low melanin production. The reaction regarding erythema is very similar.

• Very good response in both normofractionated and hypofractionated treatments. In most of the parameters measured, it has a better response than most of the creams evaluated. Our hypothesis is confirmed that the combination of Soothing Body Cream and Soothing Repairing Oil is a highly recommended protocol.
• Note: the use of the Soothing Repair Oil should not be applied before the treatment to avoid a bolus effect.

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• Elasticity: 2.8% loss from start to end of treatment. Average loss with other creams: 10%.
  EVALUATION: The usual loss in RDT treatment is much lower than that of other creams. The good response is related, in the medium term, to recovering basal elasticity as soon as possible.
• Hydration: loss of 5.66% from the beginning to the end of treatment. Average loss with other creams: 10-12%.
  EVALUATION: It is very interesting that the loss of hydration is less to avoid Grade 2 flaking.
• Melanin: 7.5% increase from start to end of treatment. Average increase with other creams: 12-18%.
  EVALUATION: An increase in melanin always occurs from the second half of the treatment and is greater in phototypes III-IV, due to the increased activity of melanocytes. Its excessive growth produces hyperpigmentation of the skin and aesthetically these spots take a long time to recover. For this reason, the excellence of the small increase.
• Erythema: 22.08% increase from start to end of treatment. Average increase for other creams: 15-25%.
  EVALUATION: In this case, the increase is very similar to the rest of the creams. An inevitable effect that is produced by the increase in vascularization. The most important thing is to stay in Grade I and avoid peeling. This is achieved with good control of hydration.

• Elasticity: 11.3% loss from start to end of treatment. Average loss with other creams: 10%.
  EVALUATION: The differential reaction between normal and hypo is marked. Very similar to the rest of the creams.
• Hydration: 2% loss from start to end of treatment. Average loss with other creams: 10-12%.
  EVALUATION: It is very interesting that the loss of hydration is less to avoid Grade 2 flaking.
• Melanin: loss 1.1% from start to end of treatment. Average increase with other creams 12-18%.
  EVALUATION: An increase in melanin always occurs from the second half of the treatment and is greater in phototypes III-IV due to the increased activity of melanocytes. Their excessive growth produces
  hyperpigmentation of the skin and aesthetically these spots take a long time to recover. Therefore, the
  excellence of the little increase.
• Erythema: 20% increase from start to end of treatment. Average increase with other creams 15-25%.
  EVALUATION: In this case the increase is very similar to the rest of the creams. An inevitable effect that occurs
  due to increased vascularization. The important thing is to stay in Grade I and avoid peeling with good care.
  hydration control.

• Normofractionated treatments: the maximum important reaction occurs in the last sessions and a few days later.
• Hypofractionated treatments: the maximum important reaction is 1 week after completion.
  In both cases, the good data provided by the protocol is very important, specifically in terms of hydration; avoiding peeling and minimal increases in melanin aesthetically. Note: It is advisable to maintain the same care in
  the following 15-20 days.

• Purifying soapy oil: Use as a normal shower gel, even as a shampoo. Essential for radiotherapy in the intimate area.
• Soothing body cream: Apply twice a day. In case of itching, redness and extreme dryness, apply as needed.
• Repairing and soothing oil: Apply 3 times a day. Important: apply just after the radiotherapy session, never before. The skin in the area to be treated must be clean of any product before the session.